Psychedelic drugs are staying up to have the ability to be antidepressant drugs. One of the more popular ones is the Ayahuasca plant that can be found in the Amazon rainforest. To prove its usefulness, a team of researchers from Brazil led by Stevens Rehen, Federal Professor of the University of Rio de Janeiro (UFRJ) and Chief Researcher at the D’Or Institute for Research and Education (IDOR), to make mini-brains in the laboratory. They want to know more about the effects of ayahuasca on the human brain. In the meantime, perhaps you also need to find out more about a reliable ayawasca retreat center in South America.
The artificial or organoid brain was grown for 45 days and divided into several groups. The first group was soaked with compounds isolated from ayahuasca, while the rest were soaked with alcohol and normal compounds.
The researchers then looked at the differences in the amount of protein to find out the effect of ayahuasca. In organoids soaked ayahuasca, protein is associated with more basic processes of memory arising. Another change is the anti-inflammatory effect which is considered an anti-depressant.
However, research published in Scientific Reports also has its limits. One of them is an organoid size which is only 5-6 millimeters, equivalent to the brain of an embryo aged 3-4 months. The researchers grew organoid only to that size because the larger brain needed nutrients and oxygen from the bloodstream. However, this means that the results of the study cannot be applied to the adult human brain.
“This is an interesting study,” said Michal Stachowiak, a researcher at the University of Buffalo, as quoted by Newsweek. “(But) I’m not sure the model was developed properly. I’m skeptical that this model can be used to reflect an adult human brain full of neurons,” he said. However, this method is not completely useless. Stachowiak said that organoid can be applied to other studies, especially diseases that infect the brain in the early stages of development, such as schizophrenia and autism.